The Global Trafficking ISAO is focused on combating human and wildlife trafficking. Anyone who is an advocate for combating human and wildlife trafficking, either as an individual or an entity, is encouraged to join.

Stakeholders generally fall into one of six stakeholder communities: Law enforcement; Non-governmental organizations (NGOs), Not for Profits (NFP), Think Tanks and other charitable entities; the private sector, the faith community, companies in industries affected by human and wildlife trafficking; governments and lawmakers, regulations makers, prosecutors, service providers, researchers; academia/researchers, those implementing or having implemented curricula on related topics; and the public, that is any persons or entities that do not fall into these categories but do care about these heinous crimes against humanity and helpless animals.